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Choroid anatomy

Anatomy & Optics

Key Points

  • •The choroid has the highest blood flow per unit tissue weight of any organ; receives 65-85% of total ocular blood flow; consists of 3 vascular layers: Haller's (large), Sattler's (medium), choriocapillaris (fenestrated capillaries) - supplies the outer 1/3 of the retina (photoreceptors + RPE)
  • •Bruch's membrane has 5 layers: RPE basement membrane, inner collagenous, elastic (central, strongest), outer collagenous, choriocapillaris basement membrane - drusen deposit between RPE BM and inner collagenous layer; CNV grows through breaks in Bruch's
  • •Blood supply: SPCAs (~15-20, posterior choroid), LPCAs (2, transit to anterior uvea, major arterial circle), ACAs (recurrent branches); drainage: 4-7 vortex veins at the equator → ophthalmic veins → cavernous sinus
  • •Choriocapillaris is arranged in lobules (each fed by 1 arteriole); fenestrations face Bruch's membrane; outer BRB is at the RPE level (not choriocapillaris); watershed zones between lobules → ischaemic vulnerability (Elschnig spots, Amalric sign)
  • •Pachychoroid spectrum: dilated Haller's vessels (pachyvessels) → RPE dysfunction → CSCR, PPE, PNV, PCV - measured by enhanced depth imaging OCT (EDI-OCT); ICGA is the gold standard for choroidal vascular imaging

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Clinical features

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