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Optic nerve anatomy

Anatomy & Optics

Key Points

  • •The optic nerve has 4 parts: intraocular (1 mm), intraorbital (25–30 mm, S-shaped), intracanalicular (6–10 mm), and intracranial (10 mm) - total ~50 mm; contains ~1.2 million RGC axons
  • •The lamina cribrosa is the primary site of glaucomatous damage; myelination stops here; it is weaker superiorly and inferiorly explaining the arcuate pattern of glaucomatous field loss
  • •Blood supply: optic nerve head from SPCAs + circle of Zinn-Haller (not CRA); CRA enters the nerve ~10–12 mm behind the globe and supplies the inner retina; pial plexus supplies the intraorbital segment
  • •The optic nerve is a CNS tract enclosed by meninges with CSF in the subarachnoid space - raised ICP causes papilledema via CSF pressure transmission along the optic nerve sheath
  • •The intracanalicular segment is most vulnerable to trauma (dura adherent to periosteum, no room for expansion); the ophthalmic artery travels through the same canal

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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