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Age-related cataract

Cataract & Refractive Surgery

Key Points

  • •Age-related cataract is the leading cause of reversible blindness worldwide, responsible for 33% of global blindness (WHO).
  • •Nuclear sclerosis causes a myopic shift ("second sight") - temporary near-vision improvement is a classic exam clue.
  • •Phacoemulsification is the gold standard; 95% achieve BCVA ≥6/12 with modern techniques (AAO PPP).
  • •PSC cataract is strongly associated with corticosteroid use and diabetes and causes symptoms disproportionate to its apparent size due to its axial location.
  • •The LOCS III system is the standard photographic grading system for classifying cataract severity in clinical trials.
  • •Complications of advanced cataract include phacomorphic glaucoma (intumescent lens), phacolytic glaucoma (leaking HMW proteins), and phacoantigenic uveitis.

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Keep reading Age-related cataract

17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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