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Phacolytic glaucoma

Cataract & Refractive Surgery

Key Points

  • •Phacolytic glaucoma is an open-angle glaucoma caused by leakage of HMW lens proteins through an intact hypermature cataract capsule - the angle is open on gonioscopy
  • •The anterior chamber is deep (not shallow) - this distinguishes it from phacomorphic glaucoma which has a shallow AC and closed angle
  • •AC paracentesis showing protein-laden macrophages on Millipore filter is the diagnostic gold standard
  • •Cataract extraction is curative - removing the offending lens eliminates the protein source and IOP normalises
  • •Pre-operative IOP control with topical and systemic agents, followed by surgery within 24–48 hours, is the standard management approach

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
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  • Risk factors and associations

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