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Normal tension glaucoma

Glaucoma

Key Points

  • •NTG = glaucomatous optic neuropathy with IOP consistently ≤21 mmHg; accounts for 30–40% of OAG in the West and up to 90% in Japan (Tajimi Study)
  • •CNTGS proved 30% IOP reduction reduces progression from 35% to 12% - IOP lowering is still beneficial despite normal baseline
  • •Disc hemorrhages are the strongest predictor of progression and are 2–3x more common in NTG than POAG
  • •MRI brain/orbits is mandatory to exclude compressive optic neuropathy (pituitary tumor), especially if age <50, pallor > cupping, or vertical midline-respecting field loss
  • •10-2 visual fields are essential - NTG threatens fixation with paracentral scotomas that may be missed on 24-2 alone

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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