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OCT in glaucoma

Glaucoma

Key Points

  • •OCT detects glaucomatous structural damage (RNFL and GCC thinning) before visual field loss appears - up to 25–40% of RGCs can be lost before SAP detects a defect.
  • •The RNFL deviation map showing wedge-shaped defects and the TSNIT profile losing its 'double hump' pattern are the hallmark OCT findings of glaucoma.
  • •The floor effect (~40–50 µm RNFL thickness) limits OCT's utility in advanced glaucoma - visual field testing becomes the primary monitoring tool in severe disease.
  • •Always check scan quality, centration, and segmentation accuracy before interpreting OCT measurements - artefacts are the most common cause of false findings.
  • •Macular GCIPL/GCC analysis complements peripapillary RNFL and may detect early macular damage missed by standard RNFL scans, especially in normal-tension glaucoma and myopic eyes.

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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