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Anterior ischemic optic neuropathy

Neuro-Ophthalmology

Key Points

  • •AION is the most common acute optic neuropathy over age 50; NAION accounts for ~90% and A-AION (GCA) for ~10%
  • •NAION presents with painless sudden visual loss on waking, altitudinal field defect, and a 'disc at risk' in the fellow eye
  • •A-AION is an ophthalmic emergency - start IV methylprednisolone 1 g/day immediately, BEFORE temporal artery biopsy results
  • •IONDT proved optic nerve sheath decompression is NOT effective for NAION and may be harmful (JAMA 1995)
  • •Jaw claudication (LR ~4.2) is the most specific historical symptom for GCA; ESR and CRP must be checked urgently in all patients >50 years with disc edema

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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