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Fourth nerve palsy

Neuro-Ophthalmology

Key Points

  • •CN4 is the only cranial nerve that exits dorsally and decussates completely at the anterior medullary velum - bilateral CN4 palsy after head trauma is due to contrecoup injury at this decussation point
  • •The Parks 3-step test (hypertropic eye → worse in which horizontal gaze → worse on which head tilt) systematically localizes the paretic muscle - combined with Bielschowsky head tilt test this is the definitive bedside diagnostic method
  • •Congenital CN4 palsy is the most common cause overall - look for head tilt on old photographs, large vertical fusional amplitudes (>3 PD), and facial asymmetry to distinguish from acquired
  • •Microvascular CN4 palsy (in patients >50 with HTN/DM) has an 85–90% spontaneous recovery rate within 3–6 months - observation is appropriate; failure to recover mandates neuroimaging
  • •Excyclotorsion >10 degrees on double Maddox rod test strongly suggests bilateral CN4 palsy - even if the hypertropia appears unilateral

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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