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Sixth nerve palsy

Neuro-Ophthalmology

Key Points

  • •CN6 palsy is the most common acquired ocular motor palsy in adults; abducens nerve has the longest intracranial subarachnoid course (~50–55 mm)
  • •Microvascular etiology (DM, HTN) is most common in adults >50; spontaneous recovery in 70–85% within 3–6 months
  • •CN6 palsy is the classic 'false localizing sign' - bilateral CN6 palsy = raised ICP until proven otherwise
  • •Gradenigo syndrome triad: CN6 palsy + V1/V2 facial pain + otorrhea (petrous apicitis from otitis media)
  • •A nuclear CN6 lesion produces an ipsilateral conjugate gaze palsy, NOT just abduction deficit (internuclear neurons also affected)

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17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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