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Seventh nerve palsy

Neuro-Ophthalmology

Key Points

  • •UMN vs LMN distinction: UMN facial palsy spares the forehead (bilateral cortical innervation of upper face) while LMN palsy affects the entire ipsilateral face including forehead - this is the single most important clinical distinction
  • •Bell palsy treatment: prednisolone 1 mg/kg/day within 72 hours of onset improves complete recovery from 64% to 83% (NNT=6) - Sullivan et al. NEJM 2007
  • •The most important ophthalmic complication is exposure keratopathy from lagophthalmos - aggressive lubrication, taping at night, and gold weight implant for chronic cases are the cornerstones of management
  • •Bilateral facial palsy should raise suspicion for Lyme disease (25% of Lyme facial palsies are bilateral), Guillain-Barre syndrome, sarcoidosis, or bilateral Bell palsy
  • •Combined CN5 + CN7 palsy is the worst-case scenario for the cornea - loss of both protective sensation (CN5) AND lid closure reflex (CN7) creates a neurotrophic + exposure keratopathy that is extremely difficult to manage

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
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  • Risk factors and associations

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