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Lacrimal gland tumors
Oculoplasty
Key Points
- •The "Rule of 50s": 50% of lacrimal gland masses are epithelial; of these, 50% are benign (pleomorphic adenoma); of malignant epithelial tumors, the most common is adenoid cystic carcinoma
- •Incisional biopsy is CONTRAINDICATED for suspected pleomorphic adenoma - tumor seeding through the pseudocapsule leads to multilocular recurrence and malignant transformation risk
- •Pain in a lacrimal gland mass = red flag for adenoid cystic carcinoma (perineural invasion of CN V1); painless slow growth = pleomorphic adenoma
- •Adenoid cystic carcinoma: Swiss-cheese (cribriform) pattern most common; basaloid (solid) pattern worst prognosis; hallmark is perineural invasion
- •CT distinguishes: smooth bony remodelling (pleomorphic adenoma) vs bony destruction (adenoid cystic carcinoma) vs moulding without bone changes (lymphoma)
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17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations