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Amblyopia

Pediatric Ophthalmology

Key Points

  • •Amblyopia affects 2–5% of children and is the most common cause of monocular vision loss in the under-70 age group (AAO PPP 2023)
  • •Crowding phenomenon (better VA with isolated optotypes than linear charts) is pathognomonic and distinguishes amblyopia from organic causes
  • •Always perform cycloplegic refraction - anisometropic amblyopia is the most commonly missed cause at screening
  • •PEDIG ATS studies: 2 hours/day patching equivalent to 6 hours for moderate amblyopia (ATS2); 6 hours/day equivalent to full-time for severe (ATS3); atropine equivalent to patching for moderate (ATS1)
  • •Stimulus deprivation amblyopia (e.g., unilateral congenital cataract) is the most severe form - surgery must occur within 4–6 weeks of life for any useful vision

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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