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Congenital corneal opacities

Pediatric Ophthalmology

Key Points

  • •The STUMPED mnemonic covers the major causes of congenital corneal opacities: Sclerocornea, Tears in Descemet, Ulcer, Metabolic, Peters anomaly, Endothelial dystrophy, Dermoid
  • •Congenital glaucoma must be ruled out first in any infant with corneal haze - look for epiphora, photophobia, blepharospasm, buphthalmos, and Haab striae
  • •Haab striae from congenital glaucoma are horizontal Descemet breaks; forceps injury causes vertical/oblique tears - a classic exam differentiator
  • •Peters anomaly presents with central corneal opacity + iridocorneal adhesions (Type I) or keratolenticular adhesion (Type II); bilateral in 80%; 50% develop glaucoma
  • •Early intervention (PK within 6–8 weeks for bilateral opacities) is critical to prevent deprivation amblyopia during the sensitive period of visual development

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
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  • Risk factors and associations

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