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Pediatric uveitis

Pediatric Ophthalmology

Key Points

  • •JIA-associated uveitis is the most common pediatric uveitis - characteristically asymptomatic, chronic, bilateral anterior uveitis ("white quiet eye") - detected only by slit lamp screening at scheduled intervals
  • •ANA-positive oligoarticular JIA with onset <7 years carries the highest uveitis risk (20–30%) and requires slit lamp examination every 3 months
  • •Amblyopia is the most preventable cause of visual loss in pediatric uveitis - media opacities (band keratopathy, cataract) and anisometropia must be identified and treated aggressively
  • •Etanercept is ineffective for JIA-associated uveitis despite controlling joint disease - use adalimumab (approved for non-infectious pediatric uveitis per SYCAMORE trial)
  • •Toxocara is the most common infectious cause of unilateral posterior uveitis in young children - critically must be differentiated from retinoblastoma
  • •Band keratopathy is pathognomonic of chronic JIA anterior uveitis - treat with EDTA chelation

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17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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