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Coats disease
Retina & Vitreous
Key Points
- •Coats disease is a sporadic, unilateral retinal telangiectasia predominantly in young boys - presenting with leukocoria, massive yellow subretinal exudation, and exudative retinal detachment
- •Most critical differential: retinoblastoma - Coats has NO calcification on CT/ultrasound; retinoblastoma calcifies in ~95% of cases
- •FFA confirms diagnosis: 'light-bulb' aneurysms, extensive leakage from telangiectatic vessels; Shields classification (stages 1–5) guides management
- •Treatment: laser photocoagulation and cryotherapy to ablate abnormal vessels; anti-VEGF as adjunct; surgery for exudative RD; enucleation if retinoblastoma cannot be excluded
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17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations