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Central retinal vein occlusion
Retina & Vitreous
Key Points
- •CRVO is the second most common retinal vascular disease; classified as non-ischaemic (75%, better prognosis) or ischaemic (25%, high NVG risk)
- •RAPD is the key bedside sign distinguishing ischaemic from non-ischaemic CRVO; FFA shows ≥10 disc areas of non-perfusion in ischaemic type
- •Macular oedema is the main cause of vision loss - anti-VEGF is first-line (CRUISE: +14.9 letters with ranibizumab at 6 months)
- •100-day glaucoma: ischaemic CRVO carries ~60% risk of NVI/NVG - monitor with gonioscopy. PRP only when NV develops (CVOS - no prophylactic PRP)
- •Always investigate for hypertension (present in 50–70%) and glaucoma; screen for thrombophilia in patients <50 years
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Keep reading Central retinal vein occlusion
17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations