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Hypertensive retinopathy

Retina & Vitreous

Key Points

  • •The Keith-Wagener-Barker classification (Grades I–IV) is the standard grading; Grade IV (disc oedema) = malignant hypertension = medical emergency
  • •Chronic changes (arteriolar narrowing, AV nicking, copper/silver wiring) are largely irreversible but do not affect vision directly
  • •Acute changes (haemorrhages, cotton-wool spots, hard exudates, disc oedema) indicate current severe/uncontrolled hypertension and are reversible with BP control
  • •Hypertensive retinopathy is an independent risk factor for stroke and cardiovascular mortality - findings should trigger systemic evaluation
  • •In malignant hypertension, reduce BP by no more than 25% in the first hour to avoid ischaemic complications

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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