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Macular hole

Retina & Vitreous

Key Points

  • •FTMH is classified by OCT-based minimum linear diameter: small ≤250 µm, medium 250–400 µm, large >400 µm. Smaller holes have better closure rates and visual outcomes
  • •Vitreomacular traction (VMT) during PVD is the primary mechanism - stage 1 VMT resolves spontaneously in ~50%; full-thickness holes require surgery
  • •Standard surgery is PPV + ILM peeling + gas tamponade with face-down positioning; closure rates >90% for small-medium holes
  • •The inverted ILM flap technique achieves >90% closure even for large holes - it has transformed outcomes for previously difficult cases
  • •Watzke-Allen sign (broken beam) is positive in FTMH and negative in pseudohole/lamellar hole - a key clinical exam distinction

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17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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