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Brown syndrome

Strabismus

Key Points

  • •Brown syndrome is a restrictive strabismus with limited elevation in adduction due to inability of the SO tendon to pass freely through the trochlea - the forced duction test is positive (mechanical restriction).
  • •The key differentiator from inferior oblique palsy is the forced duction test: positive (restricted) in Brown, negative (paretic) in IO palsy - both present with limited elevation in adduction.
  • •50% of congenital Brown syndrome improves spontaneously - observation is first-line unless significant hypotropia in primary position or head posture >15 degrees.
  • •Rheumatoid arthritis (trochleitis) is the most common systemic cause of acquired Brown syndrome; peritrochlear steroid injection is effective in 70–80%.
  • •Surgery involves SO tenotomy or SO tendon spacer (silicone expander) - spacer substantially reduces the risk of iatrogenic SO palsy compared with full tenotomy.

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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