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Duane retraction syndrome

Strabismus

Key Points

  • •Duane retraction syndrome is a congenital cranial dysinnervation disorder caused by absent VI nerve + anomalous III nerve innervation of the lateral rectus → co-contraction on adduction.
  • •The diagnostic triad is: limited horizontal movement + globe retraction on adduction + palpebral fissure narrowing on adduction.
  • •Type I (limited abduction, esotropia) is the most common type (70–80%); affects the left eye (60%), females (60%), and is usually unilateral (80%).
  • •Upshoot/downshoot on adduction is caused by the lateral rectus leash effect (mechanical), NOT inferior oblique overaction - do NOT perform IO weakening.
  • •Most patients do NOT need surgery - compensatory head turn preserves binocular vision; surgery is indicated for significant strabismus, head posture >15–20 degrees, or problematic upshoot/downshoot.

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  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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