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Moebius syndrome
Strabismus
Key Points
- •Moebius syndrome is defined by congenital, non-progressive bilateral facial (VII) + abducens (VI) palsy - mask-like facies with bilateral esotropia and limited abduction.
- •The vascular disruption theory (brainstem ischaemia from disrupted basilar artery supply to rhombomeres 4–6) is the most widely accepted aetiology.
- •Exposure keratopathy from lagophthalmos is the most important preventable ophthalmological complication - corneal protection with lubrication and tarsorrhaphy is essential.
- •Distinguished from Duane syndrome by the absence of globe retraction and the presence of facial palsy - Duane has retraction, Moebius does not.
- •Management requires a multidisciplinary team: corneal protection, strabismus surgery (BMR ± transposition), facial reanimation (gracilis free flap), feeding support, and ASD screening.
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Keep reading Moebius syndrome
17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations