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Intermediate uveitis

Uvea

Key Points

  • •Snowballs (inferior vitreous aggregates) and snowbanking (pars plana exudate) are the hallmark findings - always perform scleral depression to detect snowbanking
  • •CME is the principal cause of visual morbidity (30–50%) and drives treatment decisions - OCT is the key monitoring tool
  • •Pars planitis is a diagnosis of exclusion - the term should only be used when systemic workup is negative and snowbanking/snowballs are present
  • •In any patient >50 years with 'intermediate uveitis' refractory to steroids, vitreous biopsy to exclude primary vitreoretinal lymphoma is mandatory (IL-10:IL-6 >1)
  • •MRI brain should be ordered in all cases to rule out multiple sclerosis - especially in young women with bilateral disease

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17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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