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JIA-associated uveitis
Uvea
Key Points
- •JIA-uveitis is the most common paediatric anterior uveitis - characterised by the WHITE QUIET EYE (chronic, bilateral, non-granulomatous, asymptomatic anterior uveitis)
- •Highest risk: oligoarticular JIA + ANA positive + female + young onset (<6 years) - screen every 3 months for the first 4 years
- •Methotrexate is first-line steroid-sparing agent; adalimumab is first-line biologic (SYCAMORE trial); etanercept is NOT effective for JIA-uveitis
- •30–50% of children already have complications (band keratopathy, synechiae, cataract) at first detection - highlighting the critical importance of screening
- •Band keratopathy is the classic ocular sign of chronic JIA-uveitis - calcium deposition in Bowman layer, treated with EDTA chelation
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Keep reading JIA-associated uveitis
17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations