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Panophthalmitis
Uvea
Key Points
- •Panophthalmitis is full-thickness infection of all ocular coats (retina, choroid, sclera) with orbital tissue involvement - the most severe form of ocular infection, distinguished from endophthalmitis by proptosis
- •B-scan triad: vitreous echoes + scleral thickening + retrobulbar orbital involvement; CT shows globe enhancement, orbital fat stranding, and may reveal abscess or intracranial extension
- •Bacillus cereus (post-traumatic, soil IOFB) and Pseudomonas are the most devastating organisms; endogenous cases (Klebsiella, Aspergillus) carry systemic mortality risk
- •Evisceration is the most common definitive management - preserves scleral shell for prosthesis; preceded by IV vancomycin + ceftazidime ± intravitreal antibiotics
- •Prognosis is almost universally poor - >80% of severe/delayed cases require evisceration/enucleation; <5% retain any measurable visual function
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17 more sections are included with the Clinical plan.
- Definition
- Epidemiology
- Aetiology and causes
- Pathogenesis
- Classification
- Risk factors and associations