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Scleritis

Uvea

Key Points

  • •The Watson-Hayreh classification divides scleritis into anterior (diffuse, nodular, necrotising with/without inflammation) and posterior types
  • •Necrotising scleritis carries 25% 5-year mortality when associated with systemic vasculitis (GPA, RA) - requires urgent systemic immunosuppression
  • •Phenylephrine test distinguishes scleritis (deep vessels do NOT blanch) from episcleritis (superficial vessels blanch)
  • •~50% of scleritis patients have an underlying systemic disease - systemic workup (ANCA, RF, ANA, etc.) is mandatory
  • •Scleritis requires systemic treatment (NSAIDs, oral steroids, immunosuppression) - topical drops alone are insufficient

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17 more sections are included with the Clinical plan.

  • Definition
  • Epidemiology
  • Aetiology and causes
  • Pathogenesis
  • Classification
  • Risk factors and associations

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