Cornea · Contact lens complications

Toxic keratitis

Central Toxic Keratopathy (CTK) is a rare, acute, non-inflammatory complication most commonly linked to excimer laser surgery (LASIK, PTK). Idiopathic cases exist, and associations have been noted with contact lens use, selective laser trabeculoplasty, and topical anesthetics. Clinical features: Central stromal opacity, sometimes with striae, Minimal/no inflammation, Hyperopic shift with decreased visual acuity, OCT: "inverse dome" opacity spanning anterior to posterior stroma. Confocal microscopy: activated keratocytes, possible Descemet's membrane folding. Differential diagnosis (due to similar appearance): Contact lens-induced keratitis, Infectious keratitis, Post-PRK haze, Epithelial ingrowth, Diffuse lamellar keratitis (DLK), Pressure-induced stromal keratitis (PISK),

Contributed byDr. Priya SinghResident, BVH

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