
Dr. Priya Singh
Resident, BVH
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Cornea › Contact lens complications
Toxic keratitis
Central Toxic Keratopathy (CTK) is a rare, acute, non-inflammatory complication most commonly linked to excimer laser surgery (LASIK, PTK). Idiopathic cases exist, and associations have been noted with contact lens use, selective laser trabeculoplasty, and topical anesthetics. Clinical features: Central stromal opacity, sometimes with striae, Minimal/no inflammation, Hyperopic shift with decreased visual acuity, OCT: "inverse dome" opacity spanning anterior to posterior stroma. Confocal microscopy: activated keratocytes, possible Descemet's membrane folding. Differential diagnosis (due to similar appearance): Contact lens-induced keratitis, Infectious keratitis, Post-PRK haze, Epithelial ingrowth, Diffuse lamellar keratitis (DLK), Pressure-induced stromal keratitis (PISK),
Uvea › Tubercular uveitis
Mutton Fat KPs
Differential diagnosis should also include unusual chronic inflammatory conditions including : Sarcoidosis Syphilis Herpetic uveitis Tuberculosis Vogt-Koyanagi-Harada disease Sympathetic ophthalmia Lens-induced uveitis Brucellosis Lyme disease Leprosy Toxoplasmosis Toxocariasis Coccidioidomycosis (Valley Fever)