Dr. Muskan Shaikh
resident, GAC nagpur
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Retina Vitreous › Age-related macular degeneration
Familial Dominant Drusens
The disease is typically characterized by early-onset drusenoid deposits presenting at the posterior pole, peripapillary area, center of the macula, and along vascular arcades. The deposits are characteristically described as multiple "radially elongated" or "honeycomb pattern" small drusen in early stages, but can become indistinguishable from deposits in advanced AMD in later stages as they become larger and more confluent. Involvement nasal to optic disc is a typical feature. Pigmentary changes often occur as the disease progresses . CNVM can form, with subsequent scarring, and in advanced stages geographic atrophy can occur in the areas of confluent drusen. Early stages may have bilateral symmetric basal laminar drusen.